Entries by webadmin


Alexander, F., Eggert, S., Wiest, J.: Skin-on-a-chip: Transepithelial electrical resistance and extracellular acidification measurements through an automated air-liquid interface, Genes, 2018, 9/2, 114; doi:10.3390/genes9020114


Microphysiometry Time-resolved monitoring of metabolic activities in vitro (microphysiometry) is necessary to study the dynamic regulations of core biochemical pathways in cellular disease models. Following a brief review of recent developments in the field, this contribution presents the most important branches of current sensor-based methods of microphysiometry. The primary parameters assessed by microphysiometry are extracellular […]

Fetal bovine serum (FBS): Past – present – future

van der Valk, J., Bieback, K., Buta, C., Cochrane, B., Dirks, W., Fu, J., Hickman, J., Hohensee, C., Kolar, R., Liebsch, M., Pistollato, F., Schulz, M., Thieme, D., Weber, T., Wiest, J., Winkler, S., Gstraunthaler, G. (2018) Fetal bovine serum (FBS): Past – present – future. ALTEX – Alternatives to animal experimentation. 35, 1, 99-118. […]

LOPEC 2018

You are welcome to visit our presentation at LOPEC 2018: Low-cost biosensors with printed interdigitated graphene electrodes Thomas Velten1, Thorsten Knoll1, Axel Brenner1 Anke Schultz1, Joachim Wiest2, Renate Warmers3, Gerald Jenke3, Anna Zumbülte3, Andreas Urban4, Kris Seunarine5 1Fraunhofer-Institute for Biomedical Engineering, 2cellasys GmbH, 3Saueressig GmbH + Co. KG, 4AiCuris Anti-infective Cures GmbH, 5Haydale Limited Cell-based assays are of enormous […]

3D spheroid monitoring

Alexander F.A., Eggert S., Wiest J. (2018)  A novel lab-on-a-chip platform for spheroid metabolism monitoring, Cytotechnology, 70/1, 375-386, https://doi.org/10.1007/s10616-017-0152-x

YOU-WC10 report available

WC10-You-report — Within the 10th World Congress on Alternatives and Animal Use in the Life Sciences in Seattle, we (Annemarie Lang, Frank Schulze) organized and held the You-WC10 as a workshop aiming at young and early career scientists that already work or plan to work in the field of the 3Rs. We wanted to encourage […]


53rd Congress of the European Societies of Toxicology (EUROTOX 2017), September 10 – 13, 2017, Bratislava, Slovak National Theatre ___________________________________________________________________________________________________________ Sebastian Eggert, Joachim Wiest: Extension of the cytosensor microphysiometer test method toward cell impedance measurement The cytosensor microphysiometer test method was validated by the European Commission for Validation of Alternative Methods to identify severe and […]