DIABETES RESEARCH
Pancreatic islets, and in particular insulin producing beta-cells, can be monitored under different conditions of nutrient supply. The metabolic measurement of beta-cells or islets can provide basic information on their viability and functional capacity in regenerative medicine.
The test example shows changes in metabolic activity of the beta-cell line INS-1E when exposed to glucose concentrations mimicking physiologically low and high glucose levels in blood, i.e. under conditions which regulate insulin secretion.
