17th EUROPEAN CONGERSS ON ALTERNATIVES TO ANIMAL TESTING

Meet us at the 17th European Congress on Alternatives to Animal Testing


Dr. Joachim Wiest will give a talk entiteled “BioChip-based electrochemical platform for the label-free monitoring of living cells” at the 17th European Congress on Alternatives to Animal Testing.

EMBC 2012

cellasys presents a Minisymposium on “Monitoring of living cells” at the 34th Annual International Conference of the IEEE Engineering in Medicine & Biology Society. Speakers include Dr. Martin Brischwein, Dr. Johannes Clauss and Dr. Martin Koch.


EMBC 2012 Minisymposium “Monitoring of Living Cells” in Room Sapphire 410 on Friday 31th August 2012 from 16:30 h until 17:30 h:

I) Martin Brischwein (TU Munich, Germany): Label-Free, Sensor-Based Cell Assays: State of the Art

Cell based assays provide information to the chemical, pharmaceutical, food industries and to physicians for diagnostic and therapeutical decisions. While such assays are typically bound to the use of (optical) markers, label-free assays working with microsensor techniques have emerged.

II) Joachim Wiest (cellasys GmbH, Germany): Electrochemical Technology and Methods for Data Processing for Label Free Monitoring of Living Cells

The presented work describes various microsensor technologies which are suitable for online, marker-free, multi-parametric monitoring of living cells. Furthermore different aspects of data processing, interpretation and correlation are discussed.

III) Johannes Clauss (TU Munich, Germany): Label Free Cellular Monitoring: From in Vitro to in Vivo

Label-free monitoring technologies for biological and chemical analysis are fast growing. For in vivo analysis these label-free techniques are even more crucial than for in vitro measurement. A wireless implant system including an amperometric oxygen sensor for the human body was developed, which can be implanted next to a tumor. The sensor system is capable of continuously monitoring tissue in vivo under real-time conditions over a long period of time.

IV) Martin Koch (Feldkraft Ltd., Denmark): Manipulation of Living Cells by Employing Dynamic Fields

Living cells can be swayed by dynamic fields via magnetic nanoparticles. A hereto related procedure is the well known therapy called hyperthermia. In these treatments electromagnetic fields in our case however magnetic fields are applied.

PRESENTATION AT THE BIOSENSOR 2012

At the Biosensor 2012 in Cancun / Mexico recent applications of the IMOLA-IVD technology in combination with 3D microtissue will be presented.


The presentation is entitled: “Online monitoring of 3D hepatic microtissue using electrochemical microsensors”

BIOCHIP DATASHEET AVAILABLE

Datasheet of BioChip-C and BioChip-G in downloadsection


cellasys GmbH, a spin-out of Technische Universität München published detailed description of their micro-sensor-chips for investigation of living cells. For the first time, now the pin configuration is available to the public. Before the upcoming analytica in April 2012 the high-tech company posted the datasheet on www.cellasys.com to allow customers to use the BioChips independent of the proprietary IMOLA-IVD technology. Dr. Joachim Wiest, CEO of cellasys states: „With opening the interface description we welcome new partners to integrate our BioChips into their own devices.“ Joint developments with a partner for live cell imaging are already ongoing.

ONLINE MONITORING OF 3D HEPATIC MICROTISSUE …

… using electrochemical microsensors.


Presentation at the 3D Cell Culture 2012.

At the 3D Cell Culture 2012 from 14.03.2012 – 16.03.2012 in Zurich/Switzerland recent applications of the IMOLA-IVD technology in combination with 3D microtissue will be presented.

ANALYTICA 2012

 

 
Visit us: Hall B2, Booth 307/412

LAB-ON-A-CHIP FOR MARKER FREE MONITORING OF LIVING CELLS

Presentation at the 22nd BD-STCS Workshop in Basel.


Dr. J. Wiest will give a presentation entitled “Lab-on-a-chip for marker-free monitoring of living cells” at the 22nd-BD-STCS Workshop. The topic of the workshop is “Advanced Cell Culture Techniques for Tissue Engineering and Drug Discovery & Development”.

AN IRIDIUM-OXIDE pH SENSOR FOR CELL BASED ASSAYS

Talk regarding Iridium-oxide based pH Sensors.


At September 28th Dr. H. Grothe will give a presentation entiteled “An Iridium-oxide pH sensor for cell based assays” at the 45. Jahrestagung der Deutschen Gesellschaft für Biomedizinische Technik (DGBMT). The Sensor was developed by cellasys GmbH in Cooperation with the Heinz Nixdorf – Lehrstuhl für Medizinische Elektronik of Technischen Universität München and the Institute of Materials in Electrical Engineering 1 of RWTH Aachen University.

EXTRACELLULAR ACIDIFICATION AND CHANGES …

… in Bioimpedance of L929 cells

Meet us at the 8th World Congress on Alternatives and Animal Use in Life Sciences


… In this work extracellular acidification was compared with changes in bioimpedance of L929 fibroblasts using the IMOLA-IVD technology which was developed in the group of Prof. B. Wolf at the Technische Universität München …

At the 2011 World Congress on Alternatives and Animal Use in Life Sciences.

MOBILE BIOSENSOR FOR WATER QUALITY MONITORING

Meet us as the Africon 2011 to discuss the topic “Detection of oil in biotope water with a whole-cell biosensor system”.


Monitoring and maintaining the quality of water is important since it is one of the most important resources and the basis of all life. However, current methods are stationary or obsolete. The IMOLA system is able to measure the vitality of living cells online, marker free and in real time through a multiparametric microsensor chip. In combination with green algae as signal transducers it was elucidated how an emulsion of oil in water affects the vitality of the algae. It was shown that the system using the green algae Parachlorella kessleri as biosensor unit is suitable for mobile, online-detection of changes in water quality.

The latest advances are presented in a talk at the Africon 2011.